
The mechanism of action of carisoprodol in relieving discomfort associated with musculoskeletal disorders neuropathy has not been where can I order soma 200mg Lafayette clearly identified.
In animal studies, muscle relaxation induced by carisoprodol is associated with altered interneuronal activity in the spinal where can I order soma 200mg Lafayette cord and descending reticular formation of the brain.
Carisoprodol is a skeletal where can I order soma 200mg Lafayette muscle relaxant, centrally acting, not directly relax skeletal muscles. A where can I order soma 200mg Lafayette metabolite of carisoprodol, meprobamate, has anxiolytic and sedative. The degree to which these properties of meprobamate contribute to the safety and efficacy of carisoprodol is unknown. The pharmacokinetics of carisoprodol and meprobamate metabolite were studied in a crossover study of 24 healthy subjects (12 men and 12 women) who received a single dose of where can I order soma 200mg Lafayette 350 mg (where can I order soma 200mg Lafayette see Table 2) carisoprodol. Cmax of meprobamate was 2.5 ± 0.5 g / ml (mean ± SD) after administration of single doses of 350, carisoprodol, which is about 30% where can I order soma 200mg Lafayette of the Cmax of meprobamate (approximately 8 g / ml) after administration of a single dose of 400 mg of meprobamate. Absorption The absolute bioavailability of carisoprodol has not been determined.
The median time to maximum plasma concentration (Tmax) of carisoprodol was approximately 1.5 to 2 hours. Concomitant administration of a high-fat meal, and carisoprodol (350 mg) had no effect on the pharmacokinetics of carisoprodol. Therefore, carisoprodol can be taken with or without food. Metabolism: The major pathway of carisoprodol metabolism is the liver by CYP2C19 where can I order soma 200mg Lafayette to form meprobamate.
Нема коментара:
Постави коментар